Radiation Biodosimetry for the 21st Century
Capture Collective was born out of the world-renowned Department of Radiation Oncology at The Ohio State University. Inventor Dr. Jacob and The Ohio State University, teamed up with Ikove Capital, to bring innovative biodosimetry solutions to the market.
Capture has developed technology for a minimally invasive rapid-response testing kit for emergency and first responders (both Civilian and Government) to triage radiation exposure in the event of nuclear leakage or hostile events.
This groundbreaking innovation allows for the early detection of radiation toxicity via a rapid, affordable, highly-sensitive, simple blood test.
The patented technology was developed in partnership with The James Cancer Research Institute and the Wexner Medical Center, with millions in funding from the Department of Defense (DoD), the National Institutes of Health (NIH), NASA, and BARDA.
The James Cancer Hospital
OSU Comprehensive Cancer Center/Radiation Oncology
NIH/NIAID – (Pilot Grant – Duke RadCCORE) U19-AI067798
NIH/NIAID – (SBIR Ph1) R43AI108019-A01
DOD – CDMRP – W81XWH-15-2-0054
NASA – 80NSSC18K1691
HOW IT WORKS
30 minutes for Triage, 1-2 hours for accurate dose
(+/- 0.5 gy in 1 hour)
Minimally invasive – finger stick 1-2 drops of blood
Naduparambil K. Jacob, Ph.D.
A member of the OSUCCC – James Translational Therapeutic Program, Dr. Jacob is the co-inventor of two U.S. patents related to miRNA biomarkers for radiation biodosimetry and for monitoring bone-marrow reconstitution. His laboratory has received independent research funding from NIH, DOD and NASA. His research seeks to develop non-invasive blood/urine-based biodosimetry and therapeutic strategies for timeline intervention prior to expression of disease. His work also explores the development of novel/improved strategies for radiosensitization of cancer cells in an effort to protect normal cells and achieve a better therapeutic ratio. He has helped develop and test several small molecules that inhibit surviving protein functions in the chromosomal passenger complex and its association with Aurora-B kinase, and he is testing the efficacy of these agents. Dr. Jacob has co-authored more than 25 articles appearing in well-known science journals such as Molecular Cell, Cancer Research, Radiation Research and Molecular Biology of the Cell. He has also shared his research in international presentations, including one at the Nuclear Medical Defense Conference in Munich.
Scott is an Entrepreneur in Residence working with Ikove as a Venture Developer. Prior to Ikove, Scott was General Manager of Sales and Marketing for Bertec (Biomechanics Research Instrumentation, & Balance/Vestibular Rehabilitation). Scott has also served several venture backed, high growth companies in executive and key technology roles in the fields of Surgical Simulation, Cyber Security, IT Systems Management, and Engineering Document Management. He received his BS and MS in Mechanical and Engineering Mechanics respectively and did his research work in Biomedical Engineering with a focus on Haptics, all at The Ohio State University.
John is a Co-founder of Ikove, powering commercialization efforts at leading research institutions. Additionally, John is a Founder at Proton Enterprises, a venture development firm focused on disruptive technologies to empower entrepreneurship. John is an International Business Innovation Certified Incubator Manager, bringing a hands-on owner/operator mentality to his work, having been a co-founder of 10+ businesses. He has invested/advised over 50 technology companies and is actively involved as a board member at Nikola Labs, CWD, Cognovi Labs, eLum Technologies, ParaGen Technologies, and LEVE foundation. John graduated cum laude from Xavier University with a Bachelor’s Degree in Business Management and minor in Entrepreneurial Studies. In 2016, John was awarded the Xavier University Magis Award, recognized as an alumnus who, within 15 years of graduation, has achieved a high degree of excellence and embodies Jesuit morals and ethical values.
Ikove is a venture development company founded to pursue early-stage investments with an emphasis on technology commercialization in the Midwest. Ikove believes in unlocking the potential of technology commercialization, bringing to life disruptive technology that deserves to be shared with humanity. Ikove has founded 13 disruptive tech companies, brought 60+ IP out of research laboratories, and raised over $60MM for the portfolio, creating $200MM+ in equity value since 2015.
A team of radiological SME’s consisting of Health Physicists and experienced industry technicians who are available to support radiation safety programs at every level, whenever and wherever they are needed. Whether you need expert advice or require reliable assistance with your systems, audits, inspections or license, the Qal-Tek team of experts in regulation, operation and licensing can help.